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Brucellosis Animals

#KR-2301


Monitoring of Animal Brucellosis in Central Asia (Kyrgyzstan, Kazakhstan, Tajikistan, Mongolia and Afghanistan)

Tech Area / Field

  • AGR-DIG/Diagnostics/Agriculture
  • BIO-MIB/Microbiology/Biotechnology

Status
3 Approved without Funding

Registration date
09.08.2016

Leading Institute
Kyrgyz National Agrarian University, Kyrgyzstan, Bishkek

Supporting institutes

  • National Center of Veterinary Diagnostics, Tajikistan, Dushanbe\nKazakh Scientific-Research Veterinaty Institute, Kazakstan, Almaty

Collaborators

  • Virginia-Maryland College of Veterinary Medicine, USA, VA, Blacksburg\nChungbuk Veterinary Laboratory Service, Korea, Chungju

Project summary

The project aims to determine the extent of the prevalence of brucellosis in animals in Central Asia (Kyrgyzstan, Kazakhstan, Tajikistan, Mongolia and Afghanistan), taking into account the species structure of Brucella, and to suggest recommendations for a program to reductions brucellosis.
In the countries of Central Asia, as a result of unified territorial boundaries, common historical and socio-economic development, it is necessary to pay special attention to strategies to combat zoonotic infectious diseases, which are a problem in the region. One of the critical problems posing a threat to the health of humans and animals and causing great economic loss is brucellosis infection.
Brucellosis is endemic in the area, with high prevalence both in farm and the disease is zoonotic,. Endemic zoonoses are found throughout the world where conditions for their maintenance and spread exist, and they may occasionally give rise to epidemics. Unlike the emerging zoonoses, the endemic zoonoses fall very much into the category of neglected diseases and, as a result, some are now re-emerging health problems.
There is a high prevalence of brucellosis in humans and animals in Central Asia. The infection reccurs periodically in zones where control has been achieved at times. The epidemiology is complex and poorly understood with a number of potential reservoirs both domestic and wild.Cases of B. melitensis have been detected among cattle and saiga, and cases of B. abortus have been detected among sheep, horses and yaks. This sharing of pathogens is confirmed by molecular epidemiological studies In the territories of Kazakhstan, Tajikistan and Kyrgyzstan, the microbial landscape of the disease was studied. In the region, different biovars of B. melitensis and B. abortus have been recorded. B. melitensis has been determined to have been the causative agent of brucellosis in all cases of infected people.
This project will study the spread of brucellosis among farm animals, the dynamics of the epidemic in time and space, and zoning of the territory according to the degree of actual and potential epidemiological risk. It is important to determine the species composition of the causative agent of brucellosis in different animal species and the degree of cross-species transmission of the causative agents of brucellosis. The project will study the genetic characteristics of the causative agent of brucellosis in animals and conduct a comparative analysis of the identity of the genome depending on the territorial jurisdiction of the isolate, and will identify markers of differences. The project will study the causes and conditions of outbreaks of infection, analysis of risk factors, and recommendations about management of risk are developed.


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The International Science and Technology Center (ISTC) is an intergovernmental organization connecting scientists from Kazakhstan, Armenia, Tajikistan, Kyrgyzstan, and Georgia with their peers and research organizations in the EU, Japan, Republic of Korea, Norway and the United States.

 

ISTC facilitates international science projects and assists the global scientific and business community to source and engage with CIS and Georgian institutes that develop or possess an excellence of scientific know-how.

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