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Cancer Diagnostics by Laser

#0475


Laser-Based Complex for Early Diagnostics of Malignancies.

Tech Area / Field

  • INS-MEA/Measuring Instruments/Instrumentation

Status
3 Approved without Funding

Registration date
12.11.1995

Leading Institute
NIKIET (Sverdlovsk Branch), Russia, Sverdlovsk reg., Zarechny

Supporting institutes

  • Ural Optical and Mechanical Plant, Russia, Sverdlovsk reg., Ekaterinburg\nVNIITF, Russia, Chelyabinsk reg., Snezhinsk\nResearch and Development Institute of Oncology, Russia, Tomsk reg., Tomsk

Collaborators

  • Argonne National Laboratory (ANL) / West, USA, ID, Idaho Falls\nKinki Invention Center / Kagiya Laboratory, Japan, Kyoto\nArgonne National Laboratory (ANL), USA, IL, Argonne

Project summary

Oncological diseases are considered to be one of the main reasons of mortality in the twentieth century. There is a tendency towards increasing percentage of malignancies now. Success in treatment of oncological patients greatly depends on early recognition of the disease bearing in mind the methods available at the moment.

The problem of early cancer diagnosis is complicated by a great variety in forms of malignant tumours and absence in understending their reasons. This is the reason why scientists all over the world are thinking of new methods of diagnosing intracellular changes related to development of cancerous tumours. Optical methods based on the up-to-date laser achievements'seern to be the most perspective in this respect. The most attractive feature of these methods is non-invasiveness, i.e. the possibility to diagnose without changing the tissue (e.g., without taking biopsy, surgical intervention etc).

Besides, they allow pre-morphological diagnosis.

As a rule, to diagnose cancer at early stages oncological centres and hospitals make use of a number of various methods which add to each other since up to now there is no unique means allowing for unambiguous conclusion about early malignancies. Analysis of optical methods of diagnosis available at the moment shows that solution of the problem needs complex approach.

With this in mind, it would be very perspective to create a universal optical complex for diagnosis, which could offer wide possibilities for serious and effective studies of intracellular and intratissue biochemical processes typical of malignant growths.

Elaboration of such a complex is a further step on the way to solution of an acute problem of the World - fight against oncological diseases.

Besides, it is noteworthy that this complex together with morphological methods would yield wide possibilities for comprehensive studies of homeostasis of a man to find out the most effective diagnostic criteria.

The project involves the following:

1. To carry out a number of diagnostic studies based on a comparison of healthy and injured tissue spectra measured with laser-based optical equipment developed in Technocentre "LT".

2. Elaboration and production of a prototype of a laser-based complex for early diagnosis of malignant growths and pretumour changes.

3. Inclinic studies of oncological pathologies with the help of the prototype of a laser-based diagnosis complex and development of the correspondent medical methods.


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