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Long Term Consequences of Nuclear Tests on Bio-Objects


Revelation of Distant Consequences of Nuclear Tests Influence on Biological Objects of the Semipalatinsk Test Site

Tech Area / Field

  • BIO-RAD/Radiobiology/Biotechnology
  • BIO-MIB/Microbiology/Biotechnology
  • BIO-CGM/Cytology, Genetics and Molecular Biology/Biotechnology

3 Approved without Funding

Registration date

Leading Institute
Institute of Molecular Biology and Biochemistry (Ajtkhozhin), Kazakstan, Almaty

Supporting institutes

  • National Nuclear Center of the Republic of Kazakstan / Institute of Nuclear Physics, Kazakstan, Almaty\nKazakh National University, Kazakstan, Almaty


  • University of California, USA, CA, Davis\nLawrence Livermore National Laboratory / Environmental Restoration Division, USA, CA, Livermore

Project summary

The aim of the Project is to reveal biological markers of radionuclide pollution and define indicative signs of the various levels of radioisotope composition of nuclides in the environment using plants and microorganisms, representating the local ecosystem of the Semipalatinsk Test Site (STS).

The project includes the following stages:

- study of molecular-biological indices of plants at present state of radionuclide pollution of outer environment;
- determination of mutation changes, caused by the influence of radiation and radionuclides, reflected on genetic level and in the structure of proteins and enzymes, acting in various metabolytic processes in plant cells;
- determination of specific marker indices, formed as a result of continual irradiation in dominating associations of plants in the STS area, adapted to residence in local climatic conditions;
- development of indicative test-system for different levels of radionuclide pollution of the environment on the basis of selected plant species and microorganisms;
- creation of methodical basis of measuring radionuclide pollution of the ecosystem for elaboration of highly sensitive methods to diagnose this influence;
- study of specific composition of microorganisms of root zone of plants, growing on the STS territory;
- extraction of morphological-biochemical species of microorganisms from zones with different levels of radionuclide pollution;
creation of theoretical basis for indicative testing.


The International Science and Technology Center (ISTC) is an intergovernmental organization connecting scientists from Kazakhstan, Armenia, Tajikistan, Kyrgyzstan, and Georgia with their peers and research organizations in the EU, Japan, Republic of Korea, Norway and the United States.


ISTC facilitates international science projects and assists the global scientific and business community to source and engage with CIS and Georgian institutes that develop or possess an excellence of scientific know-how.

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