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Calcium Phosphate Bioceramics

#K-388


Calcium Phosphate Bio-Ceramics from Calcium Olygophosphates

Tech Area / Field

  • MAT-CER/Ceramics/Materials
  • MED-OTH/Other/Medicine

Status
8 Project completed

Registration date
18.08.1999

Completion date
20.10.2005

Senior Project Manager
Mitina L M

Leading Institute
Institute of Chemical Sciences, Kazakstan, Almaty

Supporting institutes

  • Kazakh Scientific Center for Quarantine and Zoonotic Diseases, Kazakstan, Almaty

Collaborators

  • Texas A&M University System / Health Science Center / Baylor College of Dentistry, USA, TX, Dallas\nChubu University, Japan, Aichi

Project summary

The project aims are:
· search of new ceramic-like biomaterials on the base of calcium olygophosphates;
· medical and microbiological tests of synthesized ceramics;
· development of simple mini-technology of bioceramic production.

Both national and world medicine needs synthetic substitutes for natural bone tissues because different diseases of bones increased last time in the world, particularly in ecological disadvantageous regions. A lot of synthetic materials are used already for production of varied bone implants, prosthetic devices, restorative and repairing materials, intended to be used for change of sick bones of humans. Materials on base of calcium phosphates, which chemical composition is close to natural bone tissues present a special interest.

Realization of this project within the framework of program ISTC will allow to create and test a series of new calcium phosphate bioceramic materials with good biocompatibility. Such materials may be used for fabrication of varied implants and prosthetic devices. It is expected that simple production technologies of both ceramics and ceramic products will be worked out. The technologies will be applied for organization of mini- production of those ceramics.

The project participants accumulated a rich experience concerning syntheses and studies of different phosphate materials. They are specialists in area of preventive maintenance and treatments of bones and stomatological diseases and in the field of microbiological explorations.

Creation of new biocompatible ceramic-like calcium phosphate materials, simple and cheap technology of their production, and organization of its mini-productions will open the real possibility for people of Kazakhstan to cure the bone diseases and correct the defects of bones. Such materials can be interesting for foreign partners as well.

It is expected that new data and knowledge about the nature of calcium phosphate ceramics and about interaction of them with living tissues will be received during the research. The participants believe that materials will be used for eliminating bone defects and for treatment of bone diseases, including stomatological diseases. The results of this project will also be used for: development of simple technologies and for organization of mini-production of bioceramics as well.

The project serves the main purposes of ISTC because it solves the following problems:


· involvement to civil activity area of specialists, who were occupied earlier in development of weapon of mass defeat;
· integration of independent research groups from Kazakhstan between them selves and with foreign partners;
· financial and technical support of useful scientific works that are directed on actual problems – treatment of spreading bone and tooth diseases;
· acquaintance with modern market relations because realization of mini-technologies will open the way of joining the scientists to commercial activity.

In this work it is planned to use a methodology and technical principles of phosphate syntheses, methods of nuclear magnetic resonance and Raman spectroscopy, thermal analysis, electron scanning microscopy, XR-diffraction, and standard technique and methodology of micro-biological and medical tests of obtained materials.


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The International Science and Technology Center (ISTC) is an intergovernmental organization connecting scientists from Kazakhstan, Armenia, Tajikistan, Kyrgyzstan, and Georgia with their peers and research organizations in the EU, Japan, Republic of Korea, Norway and the United States.

 

ISTC facilitates international science projects and assists the global scientific and business community to source and engage with CIS and Georgian institutes that develop or possess an excellence of scientific know-how.

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