Gateway for:

Member Countries

Stress Monitoring


Control of the Stressful Emotional Tension in Humans on the Basis of Heart rate Variability as a New Approach to Provide the High Quality of Human Life

Tech Area / Field

  • MED-DIS/Disease Surveillance/Medicine
  • INS-MEA/Measuring Instruments/Instrumentation

3 Approved without Funding

Registration date

Leading Institute
NPO Orion, Russia, Moscow

Supporting institutes

  • Moscow State University / Department of Biology, Russia, Moscow


  • Medical University of South Carolina, USA, SC, Charleston\nPolitecnico di Milano, Italy, Milan

Project summary

The objective of the project is:
· To create the methodological and instrumental basis for wide implementation of the heart rhythm- based stress overstrain monitoring in medical practice.

As the intensity of human activity increases day-by-day in modem world , the stress overloading grows to pose a serious threat of cardiovascular, gastrointestinal and other diseases. The world medical science makes therefore great efforts to prevent these diseases.

Recently the probability of the stress states and diseases were showed to be correlated with heart rate variability indices, such as the spread of beat-to-beat interval, spectral parameters of heart rhythm and others. Based on these scientific results, the aforenamed objective of the Project has been formulated.

The technical approaches:

· A database will be created to correlate heart rate variability indices with stress states and disease.

· Special devices should be designed for measuring the heart rate variability indices in clinical practice, as well as in everyday use. These devices should be as simple to operate as everyday tonometers and thermometers are.

The anticipated results:

The stress overstrain monitoring will be introduced into extensive medical practice. The evaluation of heart rate variability will provide the early diagnosis of stress states and enable to prevent the development of various diseases. It will also be helpful as a diagnostic tool to correct the course of treatment of cardiovascular and other diseases. Thus, the active period of human life will be extended and the life quality increased.

Potential role of foreign collaborators:

— Sergio Cerutti is Full Professor in Biomedical Engineering at the Department of Computer and System Sciences of the University of Roma "La Sapienza". He is also a lecturer of two postgraduate courses at the Medical Faculty of the Milano University dealing with informatics and medical techniques. His research activity is mainly dedicated to various aspects of the biomedical signal processing in the cardiovascular system and in the field of neuroscience. He is the author of various papers published in international scientific literature on these topics. Prof. Cerutti is a member of IEEE-AEI, IFMBE-AIIMB, IEC-CEI, and other International and National Science Associations.

— J. Phillip Saul is currently an Associate Professor at the Harvard Medical School , the Harvard-M.I.T. Division of Health Sciences and Technology, and at the Boston University. His research interests include the development and understanding of myocardial ablation techniques for transcatheter treatment of tachyarrhythmias in children, 3-dimensional cardiac electrical mapping, the study of heart rate variability, and the application of control system.

Prof. Sergio Cerutti and Prof J. Philip Saul will take part in data analysis and discussion of result, as well as in elaboration of further research proposals.


The International Science and Technology Center (ISTC) is an intergovernmental organization connecting scientists from Kazakhstan, Armenia, Tajikistan, Kyrgyzstan, and Georgia with their peers and research organizations in the EU, Japan, Republic of Korea, Norway and the United States.


ISTC facilitates international science projects and assists the global scientific and business community to source and engage with CIS and Georgian institutes that develop or possess an excellence of scientific know-how.

Promotional Material

Значимы проект

See ISTC's new Promotional video view