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Food Toxic Infections Propagation


Epizootiological, Epidemiological and Ecological Assessment of Evaluation of Food Toxic Infections in Kyrgyzstan

Tech Area / Field

  • BIO-SFS/Biosafety and BioSecurity/Biotechnology
  • AGR-DIS/Disease Surveillance/Agriculture
  • ENV-EHS/Environmental Health and Safety/Environment
  • MED-DIS/Disease Surveillance/Medicine

3 Approved without Funding

Registration date

Leading Institute
National Academy of Sciences of Kyrgyzstan / Biotechnology Institution, Kyrgyzstan, Bishkek


  • Purdue University / Animal Disease Diagnostic Laboratory, USA, IN, West Lafayette

Project summary

Diplococcal (pneumococcal, enterococcal) infection is a septic disease for all the species of livestock, causing lesions of all the organs and systems – the heart, lungs, liver, kidneys, intestines, joints, marrow and the brain. Young animals more frequently new born ones are the most susceptible to the infection.

The course of disease has acute, subacute and chronic forms. At the lack of the effective control measures and means the death of sick animals can be significant and reach about 50-80%.

A human is also susceptive to the infection and its course is in a kind of lobar (croupous) pneumonia and meningitis.

The first mentioning of diplococcal infection for calves in Kyrgyzstan was made by Prof. N.U.Tsvetkov in 1944 at the united Plenary Session of VASHNIL pisions and VASHNIL branch in Kazakhstan, Almaty where it was noted that over 1941-1943 because of paratyphoid and colibaccilus there died 34% of calves and 66% of them were lot because of diplococcal and streptococcal infections.

Biotechnology Institute of the National Academy of Sciences carried out clinical and microbiological researches of the material taken from the cows sick with endometritis and mastitis to find out the sources of diplococcal infection.

Out of 25 samples of uterus content isolation in 14 ones (56%) capsular diplococcus was found. For the calves sick with endometritis a percentage of diplococcus detection in uterus isolations was significantly higher and made up 72, 2%. When investigating uterus isolations for the cows – mothers having sick calves with diplococcal infection, a percentage of diplococcus detection was much more higher and reached 81,8%; in its turn the agent was isolated from the pathological material of sick and dead calves. Similar outcomes were obtained at the investigation of the content of the damaged parts of cow udders the calves of which got sick during the first days of their lives. Out of 24 samples in 12 ones (50%) diplococcus was found, its reisolate was isolated from sick calves.

When investigating foremilk and blood for 27 parturient cows and blood of the born calves prior to giving them foremilk capsular diplococcus was found in 22 cases (81,5%) and that testifies to transplacental infection of the calves.

At the investigation of 35 foremilk samples from calved cows in 33 ones (94%) diplococcus was found; in the collected cow milk in two facilities 365 heads in each, diplococcal culture was found in all 10 investigations; at the investigation of 48 calves under one month of age in 30 ones (62,5%) diplococcus was isolated; the agent was found in 29 samples (67,2) in blood from 43 not milking cows. When investigating urine for calves and cows having high percentage of diplococcus cases (more than 60%) in 30-38% of the cases septic diplococcus was detected.

When investigating 52 milk samples from cattle and 40 sour cream samples from 3 markets in Bishkek capital city septic diplococcus was found in 18 (34,6%) and 23 (57,5%) samples accordingly.

Diplococcus was found in 25-50% of the cases in milk and blood of female sheep and in blood of the lambs of 1-2 days of age.

Diplococcus was found in 3 yak blood samples (21,4%) out of 14 investigated ones. At the investigation of 18 woman blood samples and 7 man blood samples obtained from the Center for Family Medicine, diplococcus was found in 5 (27,7%) and 1(14,2%) samples accordingly.


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