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Multifunctional Laser Surgical Facility

#2574


The Multifunctional Laser Facility Development for Skin Surgical Procedures

Tech Area / Field

  • PHY-OPL/Optics and Lasers/Physics
  • MED-OTH/Other/Medicine
  • INS-OTH/Other/Instrumentation

Status
3 Approved without Funding

Registration date
30.07.2002

Leading Institute
VNIIEF, Russia, N. Novgorod reg., Sarov

Supporting institutes

  • Institute of General Physics named after A.M. Prokhorov RAS, Russia, Moscow

Collaborators

  • Heinrich Heine Universität Düsseldorf / Institut für Lasermedizin, Germany, Düsseldorf\nDermaHealth Systems, USA, CA, Livermore\nHumboldt Universität / Charité Universitätsklinikum / Klinik fur Dermatologie, Venerologie und Allergologie, Germany, Berlin\nNCLR (Nederlands Centrum voor Laser Research), The Netherlands, Enschede

Project summary

The object of this Project is the development of the new surgical laser facility based on pulse-repetitive СО2-laser with cross discharge, device application methods in laser skin surgery and cosmetology and clinical trials operation.

Laser skin surgery and cosmetology, laser skin resurfacing first of all, nowadays are the most impetuous developing surgery sphere. Laser cosmetology is the only area of laser application to realize completely its resources – to ablate tissue layers under rigorous control without affection of ambient regions.

At present time in laser cosmetology three types of lasers are basically used for laser skin resurfacing and neoplasm ablation:

1. Continuous wave (CW) СО2 laser with longitudinal discharge with 100 W power and pulse duration more than 1 ms.


2. Impulse solid-state erbium lasers with pulse energy up to 10 J, pulse duration about 1 millisecond and repetition rate 1-20 Hz.
3. Waveguide СО2 laser with radio-frequency injection which power is up to 1 kW and pulse duration is about 100 us.

First type lasers are widely spread and their cost is rather low ($10,000 - $30,000). However their undercapacity and sequent long impulse duration lead to considerable thermal tissue lesions and prolongation of the postoperative period.

Second type lasers secure good clinic results but because of less impulse consumption (10-times less when compare with СО2 lasers) smaller tissue layers are removed during one impulse. The cost of such lasers is $30,000 - $80,000.

Third type lasers - impulse СО2 laser with impulse duration under 100 us and power about 100 mJ are the most prospective laser facilities for surgery. The point is that in this case laser exposure provides ablation regimen, when all the laser energy is used to ablate the tissue without excess heating and thermal affection of circumflex regions. At present time to obtain emanation with necessary operating factors waveguide СО2 lasers with radio-frequency injection are used (f.i. medical facility UltraPulse 5000, Coherent firm). But these lasers are rather complicated and expensive (about 200,000 US dollars).

For СО2 laser a well-developed method of active medium stimulation by transverse volume discharge is existed. In respect to technical realization this method is much easier and cheaper than radio-frequency injection one. But as a rule, such lasers generate impulses which duration is under 1 us. One can’t use such impulses for tissue ablation because of plasma optic break-down and generation of shock and sound waves that are too vigorous. Besides there are some technical difficulties: gas mixture stability, high-capacity charge commutator (thyratron) application, gas circulation assurance, etc. that make difficulties for creation of such laser type which ought to provide lasting functioning without gas mixture and commutator changes.

RFNC VNIIEF and IGP RAS have great experience in development and production of CW and pulse-repetitive lasers (СО2 lasers among them), there are highly qualified personnel and necessary equipment to conduct this work.

IGP RAS has developed pulse-repetitive laser which design solves the main problems. This device (Patent of Russia №2118025 dated 27.06.97) uses the original scheme of charge formation with the help of rotary electrode that provides gas mixture circulation simultaneously. A rotary passive discharger is used for discharge commutation. The working mixture consist of СО2 and N2 without helium that is commonly used in such systems. The experiments indicated that this scheme ensures the necessary parameters: impulse duration – 10 us, impulse power – 70-100 mJ, repetition rate no less than 100 Hz, and gas mixture stability (107 impulses during single filling). The usable scheme allows to create such practically feasible design of medical laser which cost will be several times less than waveguide laser with analogous parameters.

Project execution will result in creation of new laser surgical facility, meeting the modern requirements, and in development of application methods in cosmetology and surgery. We estimate that the developing facility will be competitive, especially in Russia where high values of equipment constrain the use of modern techniques in medicine. Joint efforts of RFNC-VNIIEF and IGP RAS allow to solves tasks of this project.


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