Molecular Epidemiology and Molecular Biology of Enteric Yersinia
#3869
Molecular Epidemiology and Molecular Biology of Enteric Yersinia: Prevalence of a 37.5 kb DNA Segment Contributing to Pathogenicity of Yersinia Strains
Tech Area / Field
- BIO-MIB/Microbiology/Biotechnology
- BIO-CGM/Cytology, Genetics and Molecular Biology/Biotechnology
Status
3 Approved without Funding
Registration date
15.05.2008
Leading Institute
Gamalei Institute of Epidemiology and Microbiology, Russia, Moscow
Collaborators
- Canadian Food Inspection Agency, Canada, AB, Lethbridge
Project summary
Yersinia virulence factors are encoded by the genes having chromosomal or plasmid location. The plasmid designated as pVM82 is a conjugative plasmid of the enteric Yersinia that contributes to pathogenicity. It is responsible for massive outbreaks of pseudotuberculosis in the Russian Far East. The aim of the present study is to compare the 37.5 kb fragments, and determine if the plasmid contains genes responsible for virulence, in clinical isolates. We are planning to use various combinations of standard techniques in molecular biology, biochemistry and microbiology to solve this task.The International Science and Technology Center (ISTC) is an intergovernmental organization connecting scientists from Kazakhstan, Armenia, Tajikistan, Kyrgyzstan, and Georgia with their peers and research organizations in the EU, Japan, Republic of Korea, Norway and the United States.
ISTC facilitates international science projects and assists the global scientific and business community to source and engage with CIS and Georgian institutes that develop or possess an excellence of scientific know-how.
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