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State Research Center of Virology and Biotechnology VECTOR

General information

Full Name
State Research Center of Virology and Biotechnology VECTOR of the Federal Service for Surveillance in Consumer Rights Protection and Human Well-being (FSRI SRC VB VECTOR)


Address
Koltsovo, Novosibirsk reg., 630559, Russia


Phone
7+3833+366010


Email
vector@vector.nsk.su;


WWW
www.vector.nsc.ru;


ISTC Projects

  • 0413 - Prediction of Aerosol Migration
  • 0414 - Quails and Hen Embryos Production
  • 0459 - Antiviral Polyprenols of Needle Trees
  • 0689 - Toxoplasmosis Diagnostics
  • 0690 - Determination of Immunoenzyme
  • 0753 - Viable Viruses in Neolithic Remains
  • 0805.2 - Genetics and Epidemiology of Hantaviruses
  • 0868 - Virus-Specific Immunohemosorbents
  • 0940-2 - Influenza Vaccines
  • 1040 - Human Defense from Highly Toxic Agents
  • 1542 - Colagenase Ointment Preparations
  • 1554 - Novel Antidrugabuse Peptide
  • 1802 - Virus Infected Cells Identification
  • 1841 - Hepatitis B Virus Subtypes
  • 1858 - Laser Diagnostics in Cardiosurgery
  • 1911 - New form of human recombinant erythropoietin
  • 1911.2 - New Form of Human Recombinant Erythropoietin
  • 1924 - Medical Consequences of Technogenic Impacts
  • 1986 - Monoclonal and Recombinant Antibodies for the Variola Virus
  • 2163 - Antiviral Aerosol Preparations
  • 2164 - "Nanovaccines"
  • 2164.2 - "Nanovaccines"
  • 2164.3 - Nanovaccines
  • 2169 - Biogenic Atmospheric Aerosols in Western Siberia
  • 2216 - Biotreatment of Oil Sorbent
  • 2311 - The Risk of Remote Consequences of Nuclear and Chemical Technologies
  • 2339 - Experimental Models of Smallpox
  • 2452 - Epidemiological Surveillance for Human Monkeypox
  • 2516 - Software for Indoor Microclimate Control
  • 2641 - Novel Pharmaceuticals for Cancer Diagnostic and Treatment
  • 2721 - Leukemias Identification using Biochips
  • 2736 - Myxoviruses Monitoring in Seals Populations
  • 2736.2 - Myxoviruses Monitoring in Seals Populations
  • 2775 - Effect of Soot Aerosols on Animals
  • 2873 - Rabies Viruses Circulation in Western Siberia
  • 2963 - Host Cell Genes and West Nile Infection
  • 2991 - Atmosphere Contamination Monitoring Network
  • 2994 - Versatile Detection of Antibodies
  • 2998 - Influenza Vaccine
  • 3059 - Sensitivity of Blood Cells to Allergens
  • 3061 - Influenza of Birds of Western Siberia
  • 3071 - Frozen Wooly Mammoth
  • 3083 - Poliomyelitis vaccine
  • 3084 - Virus identification via terahertz radiation probing
  • 3121 - Cultivating Human Skin Cells for Transplantation
  • 3144 - Characteristics of Erythrocytes of Patients with Liver and Heart Pathology
  • 3230 - Nanocarbon electrochemical biosensors
  • 3273 - Genome of Cowpox Virus
  • 3275 - Atmospheric Microorganisms
  • 3312 - Methylation and Cervical Tumors
  • 3313 - Poxviral Immunomodulatory Proteins
  • 3347 - Measurement of Pregnancy-Associated Plasma Protein-A
  • 3348 - Agents for Immunotherapy of Tuberculosis
  • 3684 - Space Cultivation of Microorganisms
  • 3686 - Bivaccine against Variola and Hepatitis В

Tech areas

  • Vaccines / Medicine
  • Biosafety and BioSecurity / Biotechnology
  • Air Pollution and Control / Environment
  • Biochemistry / Biotechnology
  • Other / Agriculture
  • Cytology, Genetics and Molecular Biology / Biotechnology
  • Diagnostics & Devices / Medicine
  • Drug Discovery / Medicine
  • Microbiology / Biotechnology
  • Other / Biotechnology
  • Bioinformatics / Biotechnology
  • Disease Surveillance / Medicine
  • Other / Medicine
  • Optics and Lasers / Physics
  • Environmental Health and Safety / Environment
  • Industrial Biotechnology / Biotechnology
  • Biodiversity / Biotechnology
  • Monitoring and Instrumentation / Environment
  • Modelling and Risk Assessment / Environment
  • Food & Nutrition / Agriculture
  • Bioremediation / Biotechnology
  • Radiobiology / Biotechnology
  • Plant Protection / Agriculture
  • Software / Information and Communications
  • Other / Environment
  • High Performance Computing and Networking / Information and Communications
  • Geology / Other Basic Sciences
  • Particles, Fields and Accelerator Physics / Physics
  • Analytical Chemistry / Chemistry
  • Manufacturing, Planning, Processing and Control / Manufacturing Technology
  • Disease Surveillance / Agriculture
  • Extraterrestrial Exploration / Space, Aircraft and Surface Transportation
  • Manned Space Station / Space, Aircraft and Surface Transportation
  • Year 2000 Problem / Information and Communications

Brief

The State Research Center of Virology and Biotechnology VECTOR (SRC VB VECTOR, or Center) is one of Russia's largest research and production facilities whose major activities are focused on carrying out basic and applied research in a wide area of natural sciences, development and manufacture of therapeutic, preventive, and diagnostic products.

The Center's basic research is aimed at generating new scientific knowledge in the areas of molecular biology, virology, genetic engineering, biotechnology, epidemiology, and ecology to meet the needs of the nation’s economy.

The history of SRC VB VECTOR dates back to 1974 when it was established as the All-Union Research Institute of Molecular Biology. In 1985, a Research and Production Association NPO VECTOR was established on its basis that later in 1994 was awarded the status of a State Research Center.

The State Research Center of Virology and Biotechnology VECTOR now is a large research and production complex that is comprised of several research institutes, production companies, and other departments. Moreover, the Center is an associated member of a number of unions and associations.

The main asset for the Center is Russia's unique research and experimental capabilities that allow research on extremely human-and animal pathogenic viruses whereas total biosafety for the personnel involved and the environment is guaranteed. The well-trained scientists and technicians are very experienced in handling extremely hazardous pathogens and they have outstanding expertise in virology, molecular biology, genetic and cellular engineering, biotechnology, ecology, and epidemiology.

As of January 2003, the total staff of the Center amounted to 1147. Of these, 1009 are directly involved in scientific research, including 17 DSci's and 143 Ph.D.'s.

Post-graduate courses in three specialties (molecular biology, virology, and biotechnology) that were established at the Center in 1983 greatly contribute to highly skilled researchers training. A Doctorate Dissertation Council operates at SRC VB VECTOR through which 21 Doctor of Sciences and 134 Ph.D.-equal theses on the above-mentioned specialties were obtained.

A number of VECTOR scientists have been awarded State Prizes and Awards; elected members of different national academies, have honorary titles or have been awarded special scholarships.

All the Center's facilities are located in the vicinity of Siberia's city, Novosibirsk. Therefore, in its research programs the Center seeks to address some vital public health problems of the Novosibirsk region. One of the tasks is to provide the Novosibirsk oblast with blood-processing products to include immunoglobulin against tick-borne encephalitis. VECTOR collaborates intensively with city clinics on diagnosing some infectious diseases (viral hepatitis A, B, C, D, AIDS, CMV, herpes virus, toxoplasmosis) as well as expanding the applications of VECTOR-developed antivirals.

Over the last several years, the Novosibirsk Oblast Administration has been funding a number of innovation projects at SRC VB VECTOR dealing with the development of new immunobiologicals and medicinal preparations.

The State Research Center of Virology and Biotechnology VECTOR is open to collaboration with research institutions and companies in both basic research and development and manufacture of therapeutic, preventive and diagnostic products for public health and veterinary medicine. With its unique capabilities for handling viral and bacterial pathogens, the highly skilled staff of the Center are able to take part in implementing many international programs and open to collaboration.


Research

Applied research is aimed at developing new preparations for medicine and veterinary. Development of new preparations is based on the state-of-the-art technologies (including those involving genetic engineering) created at the Center:
– Technology of peptide synthesis is being used for development of peptide preparations (Lyuliberin and desmopressin) (Institute of Molecular Biology);
– Erythropoietin (Institute of Cell Cultures), tumor necrosis factor, and Subalin (Institute of Biologically Active Substances) are being developed using recombinant technology and are now undergoing preclinical and clinical trials. Completion of their development will expand the range of competitive domestic antivirals and anticancer drugs.
– Original technologies created at the Institute of Cell Cultures are used to develop new forms of drugs and vaccines (live measles vaccine for oral administration, recombinant erythropoietin for oral administration, etc.) Development of preparations suitable for oral administration is a topical problem, first, because of their easy use and, second, as they exclude any possibility of infection with viral agents, such as HIV, hepatitis B, and hepatitis C, unfortunately possible while using their injection forms.
– The biotechnological background developed at the Center allowed a new original approach to production of measles virus to be found. It involves substitution of the substrate used for cultivating the vaccine strain of measles virus (Institute of Cell Cultures). This technology allowed an alternative production of measles vaccine to be organized in Russia.

Tight interconnections between research and development are a specific feature of SRC VB VECTOR. This makes VECTOR one of the most modern scientific and production institutions both in Russia and in the World.